Larry Moe and Curley Joe. As a little kid I couldn't watch the stooges, would be distraught thinking about how it would feel to be hit in the head with a hammer, to have someone poke you in the eyes with their fingers.
I don't know if this is my favorite, but I've seen THE HIDDEN about 15 times, so it's up there. I really like the chemistry between Kyle MacLachlan and Michael Nouri.