Yes.
I worked on the short "Baptism By Food" (production sound and audio post) where the entire location was in a kitchen. It was for the Midnite Madness Film Festival, which gave you seven (7) days to make a short (midnight Friday you get your genre & general prop; you submit your final cut the next Friday by midnight). It started out with a dining room, a living room, a hallway and a front door (ext. & int.) as other "locations." It also had five characters. To save time and reduce "complications" it was decided at the script/production meeting Sunday morning to move the entire ten minutes into the kitchen and eliminate two extraneous characters. It worked out very nicely.