S16 blowups generally cost around $30k. you can save ALOT when considering the price of 35mm,, especially if you are shooting high ratios. It is better for blowup to 35mm because it has 33% more picture because of the widened canvas. It is 16x9 format natively, and is blown up to 35mm quite effortlessly by many major labs.
You should, however, consider using slower speed stocks. Try to shoot with more lights, or live with shallower depth of field.