https://www.youtube.com/watch?v=xVgWfmej7xE
Charlie Rose: We remember actor Philip Seymour Hoffman with A.O. Scott & David Denby
This has had me thinking of what I recently read in Keith Richard's autobiography. In it, he explains why some people overdose. Other users, unlike himself, tend to up and up and up the dose they take as their tolerance builds. That, first of all, is a mistake, according to Richards, who, as he describes, was careful to take a steady, maintenance dose, not escalating it. Then, they kick it for a while (like Richards did numerous times). When they go back to it, they make the deadly mistake of thinking they can take the dose they were taking when they last kicked it, when their tolerance was high. But now, after quitting for a while, their body can't take that dosage anymore. So they overdose. They ought to have started with a small dosage, as though starting over again.
I wonder if that happened here.