If you are employing people, then YOU ARE REQUIRED IN THE UNITED STATES by federal and state law to withhold certain taxes and pay certain fees such as unemployment insurance, worker's compensation and disability. Failure to withhold can result in CRIMINAL CHARGES, MASSIVE FINES, and other VERY BAD THINGS!
If someone is TRULY an independent contractor, i.e. they have complete control over their own work, HIGHLY UNLIKELY in the film world, then you can avoid withholding and issue a 1099 for IRS purposes to them and claim a deduction, but generally employees on a film set are employees and should be treated as such, hire a payroll company, it's not that expensive and some of them offer pay as you go worker's comp which may save you a bunch of money.
The other way to avoid this of course is to make every member of the crew a partner in the company that owns the production, but that is a lousy way to do business if you or investors are putting up money, and may be scoffed at a a sham transaction by regulators if the facts on the ground don't seem to show the transaction is legit!
Although I don't play an attorney on TV I am
one in NY, but this in no way is meant to create an attorney client relationship or to constitute specific legal advice, but rather is provided for general educational
purposes. Hope you find it useful.